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Pylocure Kit
Amoxicillin 500mg + Clarithromycin 500mg + Rabeprazole Sodium 20mg Tablet is used in the treatment of peptic ulcer disease.
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✅ Description:
Pylocure Kit-
Used to treat peptic ulcer disease caused by Helicobacter pylori infection.
Mechanism of Action:
- Clarithromycin kills H. pylori bacteria.
- Esomeprazole reduces stomach acid production.
- Amoxicillin prevents bacterial cell wall formation.
Allergy to its components, other antibiotics (especially penicillin), or other proton pump inhibitors.
Certain medical conditions like arrhythmias, hypokalemia, severe liver or kidney problems, heart issues, etc.
- Use with caution in children and dose adjustments may be required.
- Older individuals may not need dose adjustments.
- Avoid alcohol consumption.
- Caution while driving or operating heavy machinery if dizziness occurs.
Safety Advices
Alcohol
UNSAFE
Consumption of alcohol may increase the risk of side effects such as nausea, vomiting, and diarrhea, and worsen the health condition.
Pregnancy
CONSULT YOUR DOCTOR
Pylocure Kit is a pregnancy category C medicine and may cause harmful effects to the fetus if used during pregnancy. However, if clinically needed, your doctor may prescribe a Pylocure Kit if the benefits outweigh the risks.
Breastfeeding
CONSULT YOUR DOCTOR
If you are breastfeeding, consult your doctor before using the Pylocure Kit. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
CAUTION
Pylocure Kit may cause dizziness or drowsiness in some patients. So, do not drive or operate heavy machinery if you feel dizzy.
Kidney
CONSULT YOUR DOCTOR
In mild to moderate kidney impairment, dose adjustments may not be necessary. However, in patients with severe kidney failure, your doctor may have to adjust the dose.
Liver
CONSULT YOUR DOCTOR
In mild to moderate liver impairment, dose adjustments may not be necessary. However, your doctor may have to adjust the dose in patients with severe liver failure.
✔️ Composition
Each kit contains one Rabeprazole 20 mg tablet, two Amoxicillin 500 mg capsules, and one Clarithromycin 500 mg tablet.
✔️ Uses of
- Peptic Ulcer Disease (H.pylori Infection)
✔️ Side Effects of Pylocure Kit
Common side effects include nausea, vomiting, diarrhea, dark stools, dry mouth, and more, with most occurring in less than 3% of patients.
✔️ Quick Suggestions:
- Pylocure Kit is a combination of three medicines that treat stomach/intestinal ulcers by killing the causative bacteria.
- Finish the prescribed course of medicine, even if you start to feel better. Stopping it early may make the ulcer harder to treat.
- Stop taking the Pylocure Kit and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking it.
✔️ Indication
Pylocure Kit is indicated for eradicating H. pylori in active chronic gastric, duodenal, and gastric ulcers.
✔️ Pharmacology
- Amoxicillin acts by inhibiting cell wall biosynthesis, leading to bacterial death.
- Clarithromycin inhibits protein synthesis in susceptible organisms by binding to the bacterial ribosome.
- Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion.
✔️ Dosage & Administration of Pylocure Kit
The recommended dosage is each tablet twice daily for 7-14 days or as per the physician's advice.
✔️ Overdose Effects:
- Overdose experiences are not reported for Rabeprazole.
- Overdosing with Amoxicillin can lead to symptomatic and supportive treatment.
- Clarithromycin overdose may cause gastrointestinal symptoms.
✔️ Interaction
- Rabeprazole has limited interactions with drugs metabolized by the cytochrome P450 system.
- Clarithromycin may interact with various drugs, including theophylline.
✔️ Contraindications
This drug is contraindicated in patients with known hypersensitivity to any of its components.
✔️ Pregnancy & Lactation
- Use during pregnancy should be carefully considered based on the potential benefits and risks.
- The potential for serious adverse reactions in nursing infants should be weighed against the importance of therapy to the mother.
✔️ Precautions & Warnings
- Serious hypersensitivity reactions have been reported with Amoxicillin therapy.
- Care should be taken when administering to elderly patients.
- Adjustments may be needed in cases of severe hepatic impairment.
✔️ Storage Conditions
Store in a cool, dry place, protected from light.
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accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
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